Chronic hepatitis - Part 2: Treatment

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Active chronic hepatitis: Part 2.

THE belief that an immunological mechanism is involved in the chronic inflammatory process in the liver led to the use of corticotrophin and corticosteroid therapy for active chronic hepatitis as early as the 1950's (Waldenstrom 1950, Bearn, Kunkel and Slater 1956, Mackay, Taft and Cowling, 1956). However disagreement over the indications for treatment, doubts about its real value and concern a...

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IN 1950 Waldenstrom first drew attention to the occurrence of a form of chronic liver disease in young people, predominantly adolescent girls, in whom there was moderate jaundice, enlargement of the liver and spleen, acne, amenorrhoea and hyperglobulinaemia. The occurrence of fever, arthralgia and Cushingoid features was noted (Kunkel et al 1951, Beam et al 1956), the LE cell phenomenon was rep...

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ژورنال

عنوان ژورنال: DMW - Deutsche Medizinische Wochenschrift

سال: 2001

ISSN: 0012-0472,1439-4413

DOI: 10.1055/s-2001-15553